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Side effects that may be expected to occur from the administration of oral contraceptives include all of the following, EXCEPT:
Physicochemical factors affecting the rate and extent of percutaneous drug absorption include:
I the partition coefficient of the drug molecule
II the presence of surfactants in the formulation
III the type of ointment base
Select the drug whose major metabolites have therapeutically significant pharmacological activity:
A patient purchasing sublingual nitroglycerin tablets should be told to store the medication:
Dopamine is useful in the treatment of cardiogenic shock because it:
I selectively dilates renal and mesenteric vascular beds.
II does not induce peripheral vasoconstriction.
III decreases the force of myocardial contraction.
The fraction of bound receptors in a well-defined drug-receptor binding system is determined by:
I the equilibrium drug-receptor dissociation constant
II the free drug concentration
III the total receptor concentration
Factors that determine bioalence of two brands of a drug include:
I the taste of the preparations
II the physical appearance of the preparations
III pharmacokinetic parameters of the preparations
The side effects of isoniazid are potentialized by deficiency of which vitamin?
Which of the following statement is RIGHT regarding influenza treatment?
I- Type A influenza is best treated by amantadine and rimantadine
II- Type B influenza is best treated by oseltamivir and zenamivir
III- Influenza should not be treated with antiviral agents
Which Cytochrome P450 isozyme does not participate appreciably in drug metabolism?
Correct statements regarding mutation may include:
I- Cell division
II- Change in genotype
III- Change in DNA replication altering the gene
Mercapturic acid derivatives in phase II metabolism can result from reactions of:
Which of the following is the only polysaccharide NOT synthesized during human metabolism?
Biological catalysts responsible for supporting almost all of the chemical reactions that maintain human life process:
Antioxidants, which mechanistically act as reducing agents, include:
I ascorbic acid
II sodium bisulfite
III citric acid
The formation of glucose from non-carbohydrates sources such as lactate and Kreb’s cycle metabolites is an anabolic process called:
TESTED 18 May 2024
