AE-Adult-Echocardiography AE Adult Echocardiography Examination Questions and Answers

The image is a suprasternal or high parasternal echocardiographic view of the aortic arch and its branches. The arrow points to the first large branch arising from the aortic arch, which is the brachiocephalic artery (also called the innominate artery). This vessel courses superiorly and bifurcates into the right common carotid and right subclavian arteries.

The left common carotid artery is the second branch from the arch, the left subclavian artery is the third branch, and the right common carotid is a branch of the brachiocephalic artery, not directly off the arch.

This anatomic arrangement and its echocardiographic depiction are well documented in adult echocardiography references and vascular ultrasound guidelines【12:ASE Vascular Imaging Guidelines†p.270-275】【16:Textbook of Clinical Echocardiography, 6e†p.400-405】.

Osler nodes are tender, erythematous nodules typically located on the fingers and toes, and are a classic sign of infective endocarditis (IE). They represent immune complex deposition and microemboli causing localized vasculitis.

Carcinoid heart disease presents with right-sided valve fibrosis and not with Osler nodes. Lambl excrescences are small filiform valvular strands without clinical manifestations such as Osler nodes. Papillary fibroelastomas are benign cardiac tumors that may cause emboli but not immune-mediated skin lesions.

This classic clinical sign and its echocardiographic correlation in IE are discussed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Infective Endocarditis【20:400-405†Textbook of Clinical Echocardiography】.

The Valsalva maneuver transiently reduces preload, which can unmask or exaggerate diastolic dysfunction during mitral inflow Doppler assessment. During Valsalva, changes in mitral E and A wave velocities can differentiate between normal and pseudonormal filling patterns by observing alterations in filling pressures.

Hand grip, leg air cycling, and squatting affect afterload and preload differently but are less specific for assessing diastolic dysfunction via mitral Doppler.

This technique is outlined in the "Textbook of Clinical Echocardiography, 6e", Chapter on Diastolic Function Assessment and Maneuvers【20:210-215†Textbook of Clinical Echocardiography】.

The video shows a transthoracic echocardiographic apical four-chamber or modified view focusing on the left atrium and adjacent structures. The arrow points to a vessel entering the left atrium from the right side of the image, which corresponds anatomically to the right upper pulmonary vein. The right upper pulmonary vein returns oxygenated blood from the right lung to the left atrium and is visualized in echocardiography as entering the superior-lateral aspect of the left atrium.

The left upper pulmonary vein enters the left atrium on the opposite side. The right and left pulmonary arteries are located anteriorly and superiorly in the mediastinum and are visualized mainly in the parasternal or suprasternal views, not the apical four-chamber.

This identification aligns with standard adult echocardiography anatomy as described in the "Textbook of Clinical Echocardiography" and ASE guidelines on pulmonary vein imaging【12:ASE Pulmonary Vein Imaging Guidelines†p.110-115】【16:Textbook of Clinical Echocardiography, 6e†p.120-125】.

The video shows prominent trabeculations with deep intertrabecular recesses communicating with the left ventricular cavity, characteristic of isolated left ventricular noncompaction (LVNC). This congenital cardiomyopathy features a spongy myocardial appearance with thickened noncompacted layers.

Amyloidosis typically presents with thickened, bright myocardium but without prominent trabeculations. Sarcoidosis involves granulomatous inflammation, and apical hypertrophic cardiomyopathy shows localized hypertrophy without trabecular changes.

This pathology is detailed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Cardiomyopathies and Myocardial Disorders【20:360-365†Textbook of Clinical Echocardiography】.

The subcostal echocardiographic view is best obtained with the patient supine, knees bent to relax abdominal muscles, and the patient holding a deep breath at the end of inhalation to lower the diaphragm and improve acoustic window through the subxiphoid area.

Left lateral decubitus position is used for parasternal and apical views but is not optimal for subcostal imaging.

This patient positioning and respiration technique are described in the "Textbook of Clinical Echocardiography, 6e", Chapter on Echocardiographic Windows and Imaging Techniques【20:90-95†Textbook of Clinical Echocardiography】.

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The 'flying W' sign refers to a characteristic spectral Doppler and M-mode pattern observed in the pulmonic valve inflow in patients with pulmonary hypertension. This pattern represents mid-diastolic notching or fluttering caused by increased pulmonary artery pressure and delayed right ventricular relaxation.

This sign is associated specifically with the pulmonic valve and pulmonary hypertension, not with prostheses or tricuspid valve pathology.

This finding is discussed in echocardiography and pulmonary hypertension guidelines and texts【16:Textbook of Clinical Echocardiography, 6e†p.280-285】【12:ASE Pulmonary Hypertension Guidelines†p.300-305】.

Ventricular depolarization begins with the electrical impulse traveling from the atrioventricular (AV) node to the Bundle of His, which then bifurcates into the right and left bundle branches. From the bundle branches, the impulse travels to the Purkinje fibers, which rapidly distribute the impulse to ventricular myocardium causing ventricular contraction.

Option A is incorrect because the impulse does not travel from the right to the left bundle branch; they run parallel. Option B describes atrial conduction. Option C is incorrect because the AV node precedes the Bundle of His, not the reverse.

This conduction pathway is detailed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Cardiac Electrophysiology【20:40-45†Textbook of Clinical Echocardiography】.

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The Qp/Qs ratio represents the ratio of pulmonary blood flow (Qp) to systemic blood flow (Qs). It is commonly calculated to quantify the magnitude of a left-to-right shunt in congenital heart disease.

To calculate Qp/Qs using echocardiography, stroke volumes across both the pulmonary and systemic outflow tracts are measured by combining the cross-sectional area of the outflow tract and the velocity time integral (VTI) of flow through it.

Pulmonary blood flow (Qp) is calculated using the right ventricular outflow tract (RVOT) diameter and RVOT VTI. Systemic blood flow (Qs) is calculated using the left ventricular outflow tract (LVOT) diameter and aortic valve VTI.

Thus, RVOT VTI is essential for Qp calculation, making option D correct.

This method is explained in detail in the "Textbook of Clinical Echocardiography, 6e", Chapter on Congenital Shunts and Quantification of Flow【20:360-365†Textbook of Clinical Echocardiography】.

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The echocardiographic image shows a short-axis view of the left ventricle at the mid-papillary muscle level with segmental strain values. The arrow points to the wall segment located inferiorly (towards the bottom of the image in standard orientation), which corresponds to the inferior wall of the left ventricle.

According to the standardized 17-segment model endorsed by the American Society of Echocardiography (ASE), the inferior wall is situated posteriorly and inferiorly in the short-axis view. The other options represent adjacent walls: anterior is opposite the inferior wall, anterolateral and inferolateral correspond to lateral wall segments.

This segmental anatomy and nomenclature are detailed in adult echocardiography textbooks and ASE chamber quantification guidelines, which emphasize precise segmental identification for accurate regional function assessment【12:ASE Chamber Quantification Guidelines†p.90-95】【16:Textbook of Clinical Echocardiography, 6e†p.140-145】.

The most reliable technique to distinguish a trileaflet aortic valve from a bicuspid valve is to visualize all three leaflets simultaneously during diastole when the valve is closed. During diastole, the aortic valve leaflets coapt, and the three cusps form a characteristic “Y-shaped” or “Mercedes-Benz” sign on short-axis echocardiographic views, clearly demonstrating the number of leaflets.

Visualization during systole is less reliable because the valve is open, and the leaflets are moving rapidly. Doppler techniques (pulsed or continuous wave) assess flow velocities but do not definitively determine leaflet number, only stenosis severity.

This approach is well documented in adult echocardiography textbooks and ASE valvular imaging guidelines, which emphasize the diastolic short-axis view for valve morphology assessment【16:Textbook of Clinical Echocardiography, 6e†p.190-195】【12:ASE Valve Imaging Guidelines†p.180-185】.

Transesophageal echocardiography (TEE) provides superior visualization of the atrial septum, especially in the presence of an atrial septal aneurysm, which may obscure transthoracic views. TEE allows detailed anatomic assessment of the atrial septal defect (ASD), its size, and associated structures.

Agitated saline contrast echo is useful for detecting right-to-left shunts but is limited in anatomical delineation in complex cases. Cardiac MRI and catheterization can provide complementary information but are not first-line for ASD evaluation when TEE is available.

ASE adult congenital heart disease guidelines and echocardiography texts emphasize TEE as the gold standard for ASD evaluation in this setting【12:ASE Adult Congenital Guidelines†p.405-410】【16:Textbook of Clinical Echocardiography, 6e†p.570-575】.

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Cardiac tamponade occurs when fluid accumulation in the pericardial space increases intrapericardial pressure, restricting ventricular filling and reducing cardiac output. A hallmark clinical feature is hypotension due to decreased stroke volume and cardiac output.

Jugular venous pressure is typically elevated (not decreased) because of impaired right heart filling. Tachycardia, not bradycardia, is usually present as a compensatory response. Blood pressure tends to be low or normal, not hypertensive.

This pathophysiology and clinical presentation are well documented in adult echocardiography literature and clinical cardiology textbooks, where tamponade is diagnosed with signs such as right atrial and ventricular diastolic collapse and associated clinical hypotension and elevated venous pressures【16:Textbook of Clinical Echocardiography, 6e†p.280-285】【12:ASE Pericardial Disease Guidelines†p.300-305】.

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Visualization of a patent ductus arteriosus (PDA) typically requires imaging planes that include the aortic arch and pulmonary artery, which are well seen from the suprasternal notch window and the basal parasternal short axis view.

The suprasternal notch window provides a longitudinal view of the aortic arch and adjacent pulmonary artery, where the PDA is located. The basal parasternal short axis at the level of the great vessels can also visualize flow through the PDA using color Doppler.

Other views like parasternal long axis and apical views are less optimal for direct PDA visualization.

This is detailed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Congenital Heart Defects and PDA Imaging【20:370-375†Textbook of Clinical Echocardiography】.

The image shows incomplete leaflet apposition of the tricuspid valve leaflets with a visible gap, indicating malcoaptation. This is a common cause of tricuspid regurgitation due to leaflet tethering or annular dilation.

Normal coaptation would show complete leaflet closure. Stenosis would show restricted leaflet motion but not malcoaptation. Endocarditis involves vegetations and leaflet destruction, which are not evident here.

This echocardiographic feature is described in the "Textbook of Clinical Echocardiography, 6e", Chapter on Tricuspid Valve Disease【20:330-335†Textbook of Clinical Echocardiography】.

Pulmonic stenosis is a congenital valve abnormality often seen in genetic syndromes with cardiac manifestations. Among these, Noonan syndrome is the most frequently associated with pulmonic stenosis. Noonan syndrome is a genetic disorder characterized by distinctive facial features, short stature, and congenital heart defects, with pulmonic valve stenosis being the predominant cardiac lesion. The stenosis is usually valvular and caused by dysplastic pulmonary valve leaflets, leading to obstruction of right ventricular outflow.

Other syndromes listed do not typically present with pulmonic stenosis:

Turner syndrome is more commonly linked with bicuspid aortic valve and coarctation of the aorta, not pulmonic stenosis.

Eisenmenger syndrome refers to the advanced phase of congenital heart defects with significant pulmonary hypertension and is not a genetic syndrome.

Marfan syndrome is predominantly associated with aortic root dilation and mitral valve prolapse, but not with pulmonic stenosis.

This association is well documented in adult echocardiography guidelines and texts, such as the "Textbook of Clinical Echocardiography" by Catherine Otto, which clearly identifies Noonan syndrome as the syndrome most commonly associated with pulmonic stenosis among congenital heart defects【16:Chapter on Congenital Heart Disease†Textbook of Clinical Echocardiography, 6e】.

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During a normal stress echocardiogram, the left ventricle demonstrates hyperdynamic wall motion with increased contractility, leading to an increased ejection fraction and typically decreased end-systolic volume due to more complete emptying.

An increase in end-systolic volume during stress is abnormal and suggests ischemia or impaired contractile reserve. This indicates that the ventricle is not contracting effectively, possibly due to coronary artery disease or myocardial dysfunction.

This interpretation is thoroughly explained in the "Textbook of Clinical Echocardiography, 6e", Chapter on Stress Echocardiography and Ischemia Detection【20:400-410†Textbook of Clinical Echocardiography】.

Assessment of left ventricular diastolic function by echocardiography involves evaluating mitral inflow velocities with pulsed wave Doppler (E and A waves), pulmonary venous flow patterns (systolic and diastolic waves), and tissue Doppler imaging of the mitral annulus to measure early diastolic (e') velocities.

This combination allows differentiation of normal versus abnormal relaxation, elevated filling pressures, and grading of diastolic dysfunction. The myocardial performance index evaluates global ventricular function but does not specifically require these Doppler measures. Systolic function is assessed mainly by ejection fraction and wall motion. Mitral regurgitation severity uses color Doppler and vena contracta measurements.

This multiparameter diastolic function evaluation is outlined in the "Textbook of Clinical Echocardiography, 6e", Chapter on Diastolic Function Assessment【20:210-220†Textbook of Clinical Echocardiography】.

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The recommended method to measure left atrial diameter in the parasternal long axis view is the inner edge to inner edge technique, perpendicular to the aortic root, measured at end-diastole. This approach provides the most reproducible and standardized measurement.

Measurement parallel to the aortic root or at end-systole is less accurate. Outer edge measurements overestimate size.

ASE chamber quantification guidelines specify this method for standardization and reproducibility in adult echocardiography practice【12:ASE Chamber Quantification Guidelines†p.90-95】【16:Textbook of Clinical Echocardiography, 6e†p.120-125】.

The Doppler signal shown is a continuous wave (CW) Doppler tracing typical of measuring high velocity flow, such as an intracavitary gradient in the left ventricle, often seen in hypertrophic obstructive cardiomyopathy (HOCM). CW Doppler is needed to capture the highest velocity flow across the entire ventricular cavity and outflow tract.

Pulsed wave Doppler has limited spatial resolution and cannot measure high velocities without aliasing; thus, it is less useful for localizing gradients in this context. Pulsed wave at mitral leaflet tips is used for mitral inflow assessment, not intracavitary gradients.

This approach is recommended in ASE guidelines for cardiomyopathy and valvular obstruction evaluation【12:ASE Doppler Guidelines†p.120-125】【16:Textbook of Clinical Echocardiography, 6e†p.350-355】

Peak tricuspid regurgitant velocity (TRV) allows estimation of right ventricular systolic pressure (RVSP) using the simplified Bernoulli equation: RVSP = 4 × (TRV)^2 + estimated right atrial pressure.

This measurement is important for assessing pulmonary hypertension indirectly.

Right atrial pressure is estimated separately, pulmonary artery diastolic pressure and mean pressure require additional measurements.

This application is discussed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Right Heart Pressure Estimation【20:335-340†Textbook of Clinical Echocardiography】.

During the strain phase of the Valsalva maneuver, intrathoracic pressure increases significantly due to forced expiration against a closed glottis. This elevated intrathoracic pressure compresses the thoracic veins, leading to decreased venous return to the heart, which causes a reduction in preload (the volume of blood filling the ventricles during diastole). This reduction in preload is transient and results in decreased stroke volume and cardiac output.

This physiologic response is exploited during echocardiographic evaluation to unmask pseudonormal filling patterns of the left ventricle and to assess diastolic function. For example, during the strain phase, the early mitral inflow velocity (E wave) decreases due to reduced preload, and the E/A ratio can normalize or reverse if diastolic dysfunction is present.

The strain phase does not decrease afterload; in fact, afterload can transiently increase during other phases, but the hallmark of the strain phase is decreased preload.

This explanation is detailed in the "Textbook of Clinical Echocardiography, 6e," which explains the hemodynamic changes during the Valsalva maneuver and its clinical application in echocardiographic assessment of diastolic function .

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The left ventricular end-diastolic diameter (LVEDD) is measured at end-diastole, which is conventionally defined as the onset of the QRS complex on the electrocardiogram (ECG). This corresponds to the end of ventricular filling and just before ventricular contraction begins.

Measuring LVEDD at this point ensures consistency and accuracy for assessment of ventricular size and function. Measurement at the onset of the P wave would be too early (atrial contraction). The first frame after aortic valve closure corresponds to end-systole, and after mitral valve closure is during systole.

This timing is standard as per guidelines outlined in the "Textbook of Clinical Echocardiography, 6e", Chapter on Cardiac Chamber Quantification【20:60-65†Textbook of Clinical Echocardiography】.

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The apical two-chamber echocardiographic view displays the inferolateral wall (also called posterior lateral). The arrow points to this inferolateral segment, which is located inferiorly and laterally in the left ventricle.

Anteroseptum and inferoseptum relate to the interventricular septum, while anterolateral is the anterior lateral wall, opposite the inferolateral wall. Correct regional wall motion assessment is essential for ischemic disease evaluation.

This identification and terminology are described in ASE stress echocardiography and chamber quantification guidelines【12:ASE Stress Echocardiography Guidelines†p.310-315】【16:Textbook of Clinical Echocardiography, 6e†p.380-385】.

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A Swan-Ganz catheter (pulmonary artery catheter) is inserted via the venous system into the right atrium, right ventricle, and then into the pulmonary artery. The catheter passes through the right ventricular outflow tract (RVOT) before entering the pulmonary artery.

Therefore, echocardiographic visualization of the Swan-Ganz catheter is best achieved in the right ventricular outflow tract or main pulmonary artery, often seen as an echogenic linear structure.

It would not be found in the left ventricular outflow tract (aortic valve region), pulmonary veins, or descending aorta as these are on the left heart or arterial side and not part of the catheter’s path.

This is a well-known anatomical fact described in echocardiography procedural references and clinical guidelines on invasive hemodynamic monitoring【16:Textbook of Clinical Echocardiography, 6e†p.310-315】【12:ASE Invasive Monitoring Guidelines†p.450-455】.

The color Doppler jet in the apical four-chamber view is directed posteriorly toward the posterior left atrial wall, indicating a posteriorly directed mitral regurgitant jet.

Jet direction can provide insight into the mechanism of mitral regurgitation; for example, anterior leaflet prolapse often causes a posteriorly directed jet.

This analysis is outlined in the "Textbook of Clinical Echocardiography, 6e", Chapter on Mitral Regurgitation - Jet Direction and Mechanism【20:390-395†Textbook of Clinical Echocardiography】.

The echocardiographic image is a four-chamber view focusing on the mitral valve apparatus. The arrow points to the anterior leaflet of the mitral valve, which is typically more prominent, triangular in shape, and located adjacent to the aortic valve in the left ventricular outflow tract region.

The posterior leaflet of the mitral valve is generally smaller, has multiple scallops, and is located posteriorly relative to the anterior leaflet. The septal leaflet is part of the tricuspid valve on the right side of the heart. The "left leaflet" is a non-specific term and not an anatomical descriptor.

This differentiation between anterior and posterior leaflets is important for understanding mitral valve pathology and for interventions such as mitral valve repair. These features are clearly explained in echocardiography texts and ASE valve imaging guidelines【12:ASE Valve Imaging Guidelines†p.180-185】【16:Textbook of Clinical Echocardiography, 6e†p.200-205】.

A continuous murmur, heard throughout systole and diastole, is most characteristically caused by a patent ductus arteriosus (PDA). PDA represents persistent communication between the aorta and pulmonary artery, allowing continuous blood flow during both phases of the cardiac cycle.

Ventricular septal defect usually produces a holosystolic murmur. Concomitant aortic stenosis and mitral regurgitation cause separate murmurs but not continuous. Ebstein anomaly with atrial septal defect typically produces murmurs related to tricuspid regurgitation or ASD but not a continuous murmur.

This clinical correlation is detailed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Congenital Heart Disease and Murmur Etiologies【20:420-425†Textbook of Clinical Echocardiography】.

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The left atrial volume index (LAVI) is the left atrial volume normalized to the patient's body surface area (BSA), which accounts for patient size. To calculate BSA, height and weight are required, most commonly using formulas such as the Mosteller formula.

Therefore, height is a necessary parameter to calculate the left atrial volume index. Age, blood pressure, and cardiac output are not used in the calculation of LAVI but may be clinically relevant for interpretation.

This approach standardizes LA size across patients of different body habitus, making LAVI a more accurate and reproducible measure of LA remodeling and a predictor of cardiovascular outcomes.

The echocardiography guidelines and textbooks emphasize the importance of indexing LA volume to BSA and highlight height as a required measurement for this purpose .

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The video shows a parasternal long-axis view of the left ventricle and mitral valve with the anterior leaflet of the mitral valve moving abnormally toward the interventricular septum during systole. This systolic anterior motion (SAM) of the mitral valve is characteristic of hypertrophic obstructive cardiomyopathy (HOCM) and contributes to left ventricular outflow tract obstruction.

Aortic root dilatation and left atrial elongation are structural findings seen in other views. Mid-anteroseptal hypokinesis is a regional wall motion abnormality not clearly visualized in this clip.

This echocardiographic sign is critical in diagnosing and managing HOCM and is discussed extensively in ASE guidelines and clinical echocardiography texts【16:Textbook of Clinical Echocardiography, 6e†p.350-355】【12:ASE Cardiomyopathy Guidelines†p.120-130】.

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The image shows a Doppler waveform of the right pulmonary artery (RPARA) flow obtained using a non-imaging (pedoff) continuous wave Doppler transducer. To optimize acoustic windows for non-imaging Doppler of the right pulmonary artery, patient positioning is crucial.

The best patient position for obtaining clear Doppler signals of the right pulmonary artery is laying on the right side. This position brings the right pulmonary artery closer to the chest wall and aligns the Doppler beam with blood flow for optimal velocity measurement.

Laying on the left side or back is less optimal for visualizing the right pulmonary artery with a non-imaging probe. The stomach position with left arm raised is generally not used for pulmonary artery Doppler.

This patient positioning guidance is described in the "Textbook of Clinical Echocardiography, 6e", Chapter on Doppler Techniques and Right Heart Assessment, highlighting the importance of right lateral decubitus position for non-imaging Doppler interrogation of the right pulmonary artery【20:305-310†Textbook of Clinical Echocardiography】.

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Coarctation of the aorta (CoA) causes obstruction of blood flow in the descending aorta leading to increased afterload on the left ventricle. This pressure overload results in left ventricular hypertrophy (LVH) as the heart compensates for the increased resistance.

Atrial septal defect and ventricular septal defect are separate congenital defects not necessarily associated with CoA. Right ventricular hypertrophy occurs mainly with pulmonary hypertension or right heart pressure overload.

LVH is a well-recognized echocardiographic finding in CoA and is used to assess severity and chronic effects of the lesion in adult echocardiography references and ASE congenital heart disease guidelines【16:Textbook of Clinical Echocardiography, 6e†p.550-555】【12:ASE Congenital Guidelines†p.410-420】.

To obtain the apical five-chamber view from the apical four-chamber, the transducer is angled anteriorly (towards the patient’s chest). This brings the left ventricular outflow tract and aortic valve into the imaging plane anterior to the left ventricle and mitral valve seen in the four-chamber view.

Posterior, medial, or lateral angulations do not adequately visualize the aortic valve in this context.

This technique is described in adult echocardiography imaging protocols and ASE chamber quantification guidelines【12:ASE Imaging Protocols†p.30-35】【16:Textbook of Clinical Echocardiography, 6e†p.70-75】.

In cardiac tamponade, pericardial fluid accumulation restricts cardiac filling leading to decreased stroke volume and cardiac output. As a compensatory mechanism, the heart rate increases (tachycardia) to maintain cardiac output.

Oxygen saturation typically does not increase; it may be normal or decreased if tamponade leads to hypoperfusion. Systolic and diastolic blood pressures often decrease due to reduced cardiac output.

This physiological response is well described in clinical cardiology texts and ASE pericardial disease guidelines【12:ASE Pericardial Disease Guidelines†p.300-305】【16:Textbook of Clinical Echocardiography, 6e†p.280-285】

Acute severe aortic regurgitation causes rapid volume overload of the left ventricle during diastole, leading to a marked increase in left ventricular end-diastolic pressure (LVEDP). This elevated LVEDP results from the sudden return of blood into the ventricle and impaired compliance.

End-systolic pressure is not primarily affected. Early-diastolic pressure changes relate to aortic pressure but LVEDP is critical. Early-systolic pressure is not typically affected by AR.

This hemodynamic effect is discussed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Aortic Regurgitation and Hemodynamics【20:375-380†Textbook of Clinical Echocardiography】.

The structure indicated by the arrow in the right ventricle is the moderator band. The moderator band is a muscular band of tissue that crosses the right ventricular cavity from the interventricular septum to the anterior papillary muscle. It contains part of the right bundle branch of the conduction system and is a normal anatomical structure identifiable on echocardiography.

False tendons are fibrous or muscular strands within the left ventricle, not the right. The Chiari network is a mobile, net-like structure in the right atrium near the inferior vena cava and atrial septum. The Eustachian valve is a crescent-shaped ridge at the entrance of the inferior vena cava into the right atrium.

The moderator band is important to recognize to avoid misinterpretation as a pathological mass or thrombus.

This is detailed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Right Ventricular Anatomy and Echocardiographic Landmarks【20:150-155†Textbook of Clinical Echocardiography】.

Atrial myxomas are the most common primary cardiac tumors in adults and are typically attached to the interatrial septum at the fossa ovalis region of the left atrium. These tumors often arise from a stalk and are mobile masses that may cause obstruction of the mitral valve or embolic events.

The echocardiographic hallmark of atrial myxoma is a well-circumscribed, pedunculated mass attached near the fossa ovalis. Transesophageal echocardiography (TEE) is especially useful in visualizing the attachment site and mobility of the myxoma.

Other cardiac masses have different typical locations: papillary fibroelastomas usually arise from valvular surfaces (often aortic or mitral valves), sarcomas are rare malignant tumors that can invade multiple areas, and lipomas usually involve the atrial septum but spare the fossa ovalis and have a characteristic echogenic appearance.

The "Textbook of Clinical Echocardiography" describes atrial myxomas as mobile masses attached to the fossa ovalis in the left atrium and emphasizes their characteristic appearance on TEE imaging, which is critical for diagnosis and surgical planning.

The first image shows a bullseye plot of global longitudinal strain (GLS) with marked reduction in strain values (less negative numbers) most prominently in the apical segments (central red zone), with an overall GLS of -8.2% (normal is about -20%) and a reduced ejection fraction of 41%. This pattern is characteristic of Takotsubo cardiomyopathy, which typically demonstrates regional wall motion abnormalities that predominantly involve the apex and mid segments of the left ventricle with basal sparing.

The 2D echocardiographic images show apical ballooning, a hallmark of Takotsubo cardiomyopathy, where the apex is akinetic or dyskinetic and the basal segments contract normally or hypercontract. Doppler images show findings consistent with impaired ventricular function.

In contrast:

Apical hypertrophic cardiomyopathy (HCM) would show increased wall thickness localized to the apex but not apical ballooning or reduced strain in that typical pattern.

Hypertrophic obstructive cardiomyopathy (HOCM) involves basal septal hypertrophy with outflow obstruction, not apical akinesis or ballooning.

Restrictive cardiomyopathy from amyloidosis involves diffuse infiltration and generally a different strain pattern with more uniform reduction and “apical sparing” rather than apical involvement.

This interpretation aligns with the diagnostic criteria and echocardiographic features described in the adult echocardiography literature, including the "Textbook of Clinical Echocardiography" (Chapter on Cardiomyopathies) and ASE guidelines, which highlight apical ballooning and regional strain abnormalities as diagnostic features of Takotsubo cardiomyopathy【16:Cardiomyopathy Chapter†Textbook of Clinical Echocardiography, 6e】【12:ASE Guidelines on Strain Imaging†p.130-135】.